Green Buckeye RN

EHN: A Widely-Used Phthalate Not So Different From Banned Cousins, Rat Study Finds.
January 19, 2011, 11:06 am
Filed under: News

Jan 19, 2011

Boberg, J, S Christiansen, M Axelstad, TS Kledal, AM Vinggaard, M Dalgaard, C Nelleman and U Haas. 2010. Reproductive and behavioral effects of diisononyl phthalate (DINP) in perinatally exposed rats. Reproductive Toxicity
Synopsis by Emily Barrett and Wendy Hessler

An animal study finds for the first time that another widely used phthalate affects development when exposure occurs in the womb and early life. It is also the first to show the chemical can affect brain development, too. DINP – a phthalate that is increasingly used in plastic products – caused similar changes in the male reproductive system as other types of recently banned – but more potent – phthalates.
The male offspring had a host of reproductive changes, while females showed signs of masculinized brain development determined through behavior tests. The results suggest that – like other phthalates – DINP should be used with caution as its anti-androgenic properties may have serious health consequences.

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